The development of a homologous recombination deficiency (HRD) score to identify HR-deficient tumors.

Xiaohua Wu,Hao Wen,Zheng Feng,Lin Shao,Chenglin Liu,Hao Liu,Lu Zhang,Xinru Mao,Xiaoqian Guan,Ting Hou,Han Han Zhang,Zhou Zhang

The development of a homologous recombination deficiency (HRD) score to identify HR-deficient tumors.

2020

Xiaohua Wu
Hao Wen
Zheng Feng
Lin Shao
Chenglin Liu
Hao Liu
Lu Zhang
Xinru Mao
Xiaoqian Guan
Ting Hou
Han Han Zhang
Zhou Zhang

e18085Background: BRCA1/2 mutated cancers are homologous recombination repair (HRR) deficient and often sensitive to drugs targeting DNA repair pathway. Emerging evidences suggest tumors with mutat...

Keywords:

Bioinformatics
Homologous Recombination Deficiency
Pathology
Medicine

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