2,3-Dimethoxyindolines: A Latent Electrophile for SNAr Reactions Triggered by Indium-Catalyst

2,3-Dimethoxyindolines (DiMeOIN) have emerged as a latent electrophile in indium-catalyzed SNAr reactions. They are easily obtained from commercially available indoles and allowed the access to 3-substituted indoles. The reaction proceeds via SNAr reactions of in situ-generated 3-methoxyindoles. Formation of C2-substituted indoles was also possible utilizing the C2-nucleophilicity of DIMeOIN. Our protocol is user friendly as DiMeOIN is a bench-stbale easy-to-handle crystalline umpoled reagent.