692Prognostic Value of Inflammatory Markers during Treatment of Prosthetic Joint Infections

• Arthroplasty is a cost-effective treatment for arthritis, but is complicated by a 1% incidence of Prosthetic Joint Infections (PJI). • During treatment of osteomyelitis or PJI, the inflammatory markers : Erythrocyte Sedimentation Rate (ESR) and Creactive protein (CRP) are expected to decrease. • The role of ESR and CRP in predicting outcome of prosthetic joint infections (PJI), treated with a 2-stage exchange, has been inconclusive. • There was a trend towards higher mean CRP value among patients who failed treatment (mean CRP 11.35 vs 4.13 mg/dL, p-value 0.054). • There was no significant difference in mean ESR (p = 0.50), change in ESR (p = 0.19) or change in CRP (p = 0.30) between the 2 groups. • Even though the difference was not significant, last value ESR and CRP were twice as high in the failure group. • No other predictors of treatment failure were identified.