Research directions in paroxysmal nocturnal hemoglobinuria

Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is a non-neoplastic hematopoietic stem cell disorder that can produce a life-threatening syndrome of hemolysis, thrombosis and bone marrow failure. The pathophysiology and models of PNH evolution were debated at a recent workshop**The Paroxysmal Nocturnal Hemoglobinuria Workshop was held at Bethesda, MD, USA on 24–25 September 1998..