Method for producing extracellular matrix membrane derived from biocompatible porcine cartilage capable of regulating in vivo decomposition rate and physical properties, and composition for preventing adhesion containing extracellular matrix derived from porcine cartilage as active ingredient

2017 
The present invention relates to a method for producing an extracellular matrix membrane derived from biocompatible porcine cartilage capable of regulating an in vivo decomposition rate and physical properties, and a composition for preventing adhesion containing an extracellular matrix derived from porcine cartilage as an active ingredient. Despite high biocompatibility as a natural material, there is an application limit because an extracellular matrix of a cartilage tissue has poor physical properties such as a short decomposition time. Thus, a method for improving the physical properties through physical and chemical treatment thereof has been developed. In the present invention, an extracellular matrix derived from porcine cartilage is treated with physico-chemical methods to produce various types of biomaterials, and it has been confirmed that a cartilage-specific function is retained in spite of the physico-chemical treatment. Also, the present invention can be utilized as an anti-adhesion agent having excellent in vivo stability and an anti-adhesion effect using the extracellular matrix material derived from porcine cartilage.
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