Gene regulatory circuitry of plant-environment interactions: scaling from cells to the field.

Abstract Plant growth and development is the product of layers of sensing and regulation that are modulated by multifactorial environmental cues. Innovations in genomics currently allow gene regulatory control to be quantified at multiple scales and high resolution in defined cell populations and even in individual cells or nuclei in plants. The application of these ‘omic technologies in highly controlled, as well as field environments is revolutionizing the recognition of factors critical to spatial and temporal responses to single or multiple environmental cues. Within and pan-species comparisons illuminate deeply conserved circuitry and targets of selection. This knowledge can benefit the breeding and engineering of crops with greater resilience to climate variability and the ability to augment nutrition through plant–microbial interactions.