TBSOTf-promoted versatile N-formylation using DMF at room temperature

Masayoshi Sakurai,Rina Kawakami,Nobuhiro Kihara

TBSOTf-promoted versatile N-formylation using DMF at room temperature

2019

Masayoshi Sakurai
Rina Kawakami
Nobuhiro Kihara

Abstract Hydrazides and amines were N -formylated by DMF in the presence of tert -butyldimethylsilyl triflate (TBSOTf) at room temperature, in good to excellent yields.

Keywords:

Formylation
Chemistry
Organic chemistry
Trifluoromethanesulfonate

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