The effects of breast cancer treatment on cognitive functions
2008
11531 Background: We have started a longitudinal study to investigate if a) the effects of being given a breast cancer (bc) diagnosis may affect cognitive functions in women, b) if adjuvant therapy may have detrimental effects on cognition, c) if subjects with substantial cognitive impairment after therapy may benefit from a cognitive training program. Methods: The study is dimensioned for 140 subjects. The subjects are recruited consecutively and prospectively from the mammography-screening program at Sodersjukhuset, Stockholm. According to the results of the diagnostic process the patients are divided in two main groups by “biological” randomization; healthy subjects and women with bc (n=70 in each group). All participants are examined by a web-based battery of neuropsychological tests at four times: at inclusion and before diagnosis, after diagnosis (two months), after treatment (six months), and follow-up after an additional three months. Subjects who score one standard deviation below the mean compar...
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