Potent Inhibitory Effects of Type I Interferons on Human Adrenocortical Carcinoma Cell Growth

Peter M. van Koetsveld,Giovanni Vitale,Wouter W. de Herder,Richard A. Feelders,Katy van der Wansem,Marlijn Waaijers,Casper H. van Eijck,Ernst-Jan M. Speel,Ed Croze,Aart Jan van der Lely,Steven W. J. Lamberts,Leo J. Hofland

Potent Inhibitory Effects of Type I Interferons on Human Adrenocortical Carcinoma Cell Growth

2006

Peter M. van Koetsveld
Giovanni Vitale
Wouter W. de Herder
Richard A. Feelders
Katy van der Wansem
Marlijn Waaijers
Casper H. van Eijck
Ernst-Jan M. Speel
Ed Croze
Aart Jan van der Lely
Steven W. J. Lamberts
Leo J. Hofland

Context:Adrenocortical carcinoma (ACC) is a rare tumor with a poor prognosis. Despite efforts to develop new therapeutic regimens for metastatic ACC, surgery remains the mainstay of treatment. Interferons are known to exert tumor-suppressive effects in several types of human cancer.

Keywords:

Cancer
Adrenocortical carcinoma
Adrenal Cortex Carcinoma
Interferon type I
Cell growth
Cell cycle
Internal medicine
Endocrinology
Cytokine
Interferon
Medicine
Interferon beta-1a

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