O sistema imunológico e a autoimunidade

mechanisms, having a great importance in the protection against pathogens and infectious agents. Some disorders and failures may occur in the defense process, either by antigen presenting cells, antibodies or by failures in other mechanisms. One of the main consequences of these failures is the development of autoimmune diseases that can worsen over time. Thus, understanding the functions and mechanisms of antibody production capable of triggering autoimmune responses is of great relevance when the organism itself has negative consequences for certain organs and / or tissues. There are many studies of autoimmunity related to only one type of disease. Because it is a complex system, this work has provided an understanding about the functioning of the immune system and the performance of its cells, as well as informing the main reasons that cause autoimmune diseases. Keywords: Oxidative stress. Homeostasis. Tolerance.