Topically administrable compositions with an external active ingredient depot formation, their preparation and their use

The present invention relates to topically administrable compositions, which are characterized by a content of one or more poorly soluble active agents, one or more water-soluble / water-dispersible nonionic surfactants with an HLB value of at least 8 and which have water or a water-alcohol mixture. DOLLAR A With such compositions, it is surprisingly possible to bring an external active ingredient depot formation, particularly in the application. Characterized undesirable side effects which are normally avoided by the administration of such active ingredients in systemic, ie resorbing shape occur, and a locally targeted drug release can be facilitated.