Musculoskeletal applications of hyaluronan and hylan: potential uses in the foot and ankle

Abstract Hyaluronan is unusual because it can be used as a highly biocompatible and noninflammatory implant material with mechanical properties that can be customized by altering the polymer configuration. This article suggests that there may be numerous applications in the foot and ankle, including treatments for arthritis, soft-tissue augmentation, and ulcerations.