Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

The authors used chronic two-photon calcium imaging to record activity in primary whisker somatosensory cortex neurons projecting to secondary somatosensory or primary motor cortex while mice learned a texture discrimination task. Learning-related changes in primary somatosensory cortex enhanced sensory representations in a pathway-specific manner and provided downstream areas with task-relevant information for behavior.