A kind of DNA encoding library of molecules and method for screening compound

The invention discloses a kind of DNA encoding library of molecules and method for screening compound.A kind of DNA encoding library of molecules, it, which introduces one, has the short chain DNA of 8~12 bases, and described short chain DNA one end has photo-crosslinking group.Use the screening technique of the DNA encoding library of molecules of the present invention so that protein target is not required to purifying and immobilized, and can directly apply to the drug target that other methods such as memebrane protein, protein complex, living cells, pathological tissue can not be applied.