Expression Levels of Enzymes Metabolizing an Anticancer Drug Ellipticine Determined by Electromigration Assays Influence its Cytotoxicity to Cancer Cells - A Comparative Study

1 Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-128 40 Prague 2, Czech Republic 2 Department of Pediatric Hematology and Oncology, 2 nd Medical School, Charles University and University Hospital Motol, V Uvalu 84, CZ-150 06 Prague 5, Czech Republic 3 Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic 4 Central European Institute of Technology, Brno University of Technology, Technicka 3058/10, CZ616 00 Brno, Czech Republic 5 Division of Preventive Oncology, National Center for Tumor Diseases, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69 120 Heidelberg, Germany * E-mail: stiborov@natur.cuni.cz