Effects of lifelong restricted feeding on complex maze performance in rats

Male Wistar rats reared on a regimen of every-other-day (EOD) feeding (24% protein) since weaning were compared in complex maze learning at 30 mo of age to young (6 mo) and old (22 mo) ad libitum (AL) fed groups. Maze learning performance for the aged, EOD-fed group was equivalent to that of young AL-fed rats, and superior to that of aged AL-fed rats.