Genomic amplification of CDK4 in dedifferentiated liposarcomas as a predictive biomarker for microtubule disrupting agents.

2018 
11581Background: Dedifferentiated liposarcoma (DDLPS) represents a common but morbid subtype of sarcoma. Microtubule disrupting agents (MDA), including eribulin and taxanes, disrupt the cell cycle ...
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