Multiple Intrauterine Fractures – Review of two cases of Osteogenesis Imperfecta Congenita

Background: Osteogenesis Imperfecta (OI) is an uncommon congenital abnormality of the connective tissues in which diagnosis and management pose big challenges especially in Low Income and Medium Countries (LIMC). The aim is to draw attention to the rareness of an uncommon congenital lesions. Methods: Two cases of OI were seen at birth and managed in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria. Result: One of the babies died shortly after birth while the other baby was managed and discharged. She was being followed up until the parents stopped coming for follow-up visits. She eventually died at home after series of repeated admissions and management for respiratory tract infections. Conclusion: A high index of suspicion is needed prenatally. When detected at birth, parents are to be educated on the multidisciplinary approach of management, challenges and possible outcome as there is yet no cure of this condition.