Вивчення протимікробної активності нової комбінованої мазі з етонієм в умовах in vivo

The investigation of antimicrobial activity of new ointment with aethonium using the model of purulent necrosis process in rats against exciters of wound infection (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans) and the comparison of its efficiency with ointments Laevomecol and Inflarax was carried out. According to the results of experiment it was established that the ointment with aethonium has an expressed antimicrobial effect shows the absent of microbial contamination and decrease of the term of healing to 7 days when the reference drugs promoted healing to 5 days as compared with the group of control pathology. So, the new developed ointment with aethonium is a perspective subject for further pharmacological investigations with a view to treatment of purulent wounds.