Fabrication of a trans-scale bimetallic synergistic enhanced Raman scattering substrate with high surface-enhanced Raman scattering activity

A novel enhanced Raman scattering substrate was fabricated using a vacuum-deposited Ag island film on Au film inverted pyramid pits (period is 2 μm). This trans-scale bimetallic synergistic enhanced Raman scattering (TBSERS) substrate was optimized for the detection of bisphenol A, and the detection limit can be as low as 0.5 ppm by this method.