Diastereoselective Synthesis of Highly Functionalized cis-1-Oxadecalines via 6-endo-tet-Cyclizations of 2-C-Branched Sugars.

The title compounds (IV) are obtained via zinc mediated Barbier reaction of pyranosides (I) with aryl aldehydes followed by FeCl3 catalyzed highly stereoselective 6-endo-tet cyclization.