Catalytic Asymmetric [4+1] Spiroannulation of α-Bromo-β-naphthols with Azoalkenes by an Electrophilic Dearomatization/S RN 1-Debromination Approach

An enantioselective [4+1] spiroannulation of α-Bromo-β-naphthols with azoalkenes has been developed for the one-step construction of a new class of pyrazoline-based spirocyclic molecules. Using chi...