104: Optimization of competences in obstetrical emergencies: a place for simulation training?

partum compared to the non-pregnant controls with mean TLR 1 expression being 78% (p 0.001) above the non-pregnant control level. CONCLUSION: TLR 1 is elevated during pregnancy and postpartum in uncomplicated pregnancies. Since TLR 1 ligands are specifically associated with bacteria, we hypothesize that basal expression of TLR 1 increases following transient exposure to bacteria at delivery and remains elevated into the postpartum period. Postpartum TLR 1 levels have not yet returned to non-pregnant control levels suggesting that immune system adaptations persist beyond the prototypical puerperal stage. This information may be useful for future studies evaluating TLR 1 and preterm labor.