Synthesis, Spectral Characterization, Antimicrobial and Theoretical Calculation of Some 4-(tosylamino)benzohydrazide Derivatives
2018
The novel synthesis of benzohydrazide derivatives were synthesized by condensation reaction of 4- (tosylamino)benzohydrazide and substituted benzaldehyde. The synthesized compounds were characterized by IR, NMR and Mass spectral analysis. The benzohydrazide derivatives 1-4 were tested for antibacterial and antifungal activities. HOMO-LUMO analysis were carried out theoretically using Gaussian-03 package at DFT/B3LYP/6_31G (d, p) method. Dipole moment (D), polarisability (α), and hyperpolarisability (β) values show that the synthesized molecules possess electronic properties.
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