Pathogenesis, Histopathology, and Classification

Proliferative vitreoretinopathy, or PVR, is a term adopted in 1983 for describing a complication occurring after some retinal detachments (RD) [1]. PVR develops in 5–10% of RD, and although it can occur spontaneously, before surgery, it is commonest after it [2]. Pathogenesis, in the original description, was focused on the formation of membranes in both surfaces of the retina, but more recently, the existence of intraretinal changes have been added as the more severe form of PVR [3].