P-81SECONDARY BENEFITS OF ALCOHOL REDUCTION WITH NALMEFENE

The opioid system modulator nalmefene reduce average daily total alcohol consumption, number of heavy drinking days, and improve liver function and clinical status in alcohol-dependent patients. We investigated the effect of alcohol reduction with nalmefene 18 mg on alcohol dependence features, drinking consequences, and mood in two 6-month randomized, double-blind, placebo-controlled, studies (NCT00811720; NCT00812461) in alcohol-dependent patients. …