Prevalence of Hyper Amylasemia and Acute Pancreatitis in Organophosphate Poisonings

Objective: To determine the frequency of hyperamylasemia and acute pancreatitis following organophosphate poisoning. Methodology: This is a cross sectional study conducted at the Medicine Department, B.S. Medical College, West Bengal during the period of six months from 16th June 2012 to 15th June 20013. All patients of both sexes and ages above 12 years admitted with a positive history of organophosphate poisoning (OP) were included in the study. A special Proforma was designed to enter all the collected data containing the basic information about the patient, history of recent event and the past history, physical examination and the relevant investigations like complete blood count, serum amylase and lipase, alanine aminotransferase (ALT), lactate dehydrogenase (LDH),ultrasound abdomen CT abdomen(where needed). Result: Among 96 patients, hyperamylasemia was found in 30 (31.25%) patients. Acute pancreatitis was seen in 6 (6.25%) patients. Conclusion: Hyperamylasemia is more frequently seen in organophosphate poisoning while six patients proved to have acute pancreatitis as a complication.