Protein–ligand interaction-guided discovery of novel VEGFR-2 inhibitors

Yanmin Zhang,Mingliang Zhang,Yuchen Wang,Yuanrong Fan,Xingye Chen,Yan Yang,Yi Hua,Wuchen Xie,Tao Lu,Weifang Tang,Yadong Chen,Haichun Liu

Protein–ligand interaction-guided discovery of novel VEGFR-2 inhibitors

2019

Yanmin Zhang
Mingliang Zhang
Yuchen Wang
Yuanrong Fan
Xingye Chen
Yan Yang
Yi Hua
Wuchen Xie
Tao Lu
Weifang Tang
Yadong Chen
Haichun Liu

As an effective target in abnormal angiogenesis-related tumor treatment, VEGFR-2 has small-molecule inhibitors of various scaffolds being approved for treating diseases such as renal carcin...

Keywords:

VEGF receptors
Protein ligand
Biochemistry
Chemistry
Cancer research
tumor therapy
renal carcinoma

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