Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan

Richard T. Clements,Alexander Vang,Ana Fernandez-Nicolas,Nouaying R. Kue,Thomas Mancini,Alan R. Morrison,Krishna Mallem,Danielle J. McCullough,Gaurav Choudhary

Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan

2019

Richard T. Clements
Alexander Vang
Ana Fernandez-Nicolas
Nouaying R. Kue
Thomas Mancini
Alan R. Morrison
Krishna Mallem
Danielle J. McCullough
Gaurav Choudhary

Background: Angiotensin II has been implicated in maladaptive right ventricular (RV) hypertrophy and fibrosis associated with pulmonary hypertension (PH). Natriuretic peptides decrease RV afterload...

Keywords:

Cardiology
Angiotensin II
Angiotensin receptor
Afterload
Renin–angiotensin system
Neprilysin
Internal medicine
Medicine
Muscle hypertrophy
Sacubitril, Valsartan
Pulmonary hypertension

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