Radiofrequency, Infrared, and Other Technologies for Drug Delivery

“Drug delivery” or permeation of drugs through the skin has aroused great interest of dermatologists in the last years. Lasers, ablative radiofrequency, and micro-needling are used to promote drug penetration through this technique. Several drugs and cosmeceuticals have been described for use in drug delivery. Among them, the most studied are MAL, ALA, 5-FU to treat the cancer field, and pre-neoplastic lesions with excellent results. Other indications include photodamaged skin, stretch marks, scars, melasma, and alopecia. In this chapter, we will discuss the procedure for many different indications, their results, and limits.