Changes in the physical functions and health-related quality of life of elderly patients with lung cancer undergoing video-assisted thoracoscopic surgery

Introduction: Video-assisted thoracoscopic surgery (VATS), which is considered minimally invasive, has recently become a standard operative procedure for lung cancer. However, it is not clear how VATS affects physical functions and health-related quality of life (HRQOL). The purpose of this prospective study was to clarify the effects of VATS on physical functions and HRQOL in elderly patients with lung cancer. Methods: Elderly participants with lung cancer were recruited (n = 30; mean ± standard deviation age, 72.3 ± 7.2 years). We measured physical functions (pulmonary function, respiratory muscle strength, grip strength, knee extension strength, timed up and go test, 6-min walking test, and cardiopulmonary exercise test) and HRQOL (short-form 36-item health survey) preoperatively, on the 6th postoperative day, and 1 month postoperatively. Results: The median hospital stay was 8.0 days (range, 5.0–21.0). Pulmonary function decreased by VATS (Forced Vital Capacity: 2.67 vs. 2.27 L, p < 0.001). Peak VO2returned to the preoperative value 1 month after the VATS (peak VO2: 15.4 vs. 14.9 mL/kg/min, p = 0.307). The HRQOL significantly decreased after the VATS, and there were no significant improvements. Conclusion: Education and rehabilitation with a focus on HRQOL is necessary in patients undergoing VATS.