Assessment of Relationship Between Cardiovascular Risk and Risk of Development of Diabetes Mellitus

AIM: to analyze interrelationship between cardiovascular risk (CVR) and risk of development of diabetes mellitus (DM) in a cohort of working age men. MATERIAL AND METHODS: We enrolled in this study 300 men aged 40-59 years with more or equal 1 risk factors. Examination included questionnaire, standard clinical, instrumental, and laboratory studies. CVR and risk of developing DM was estimated using European SCORE scale and The Finnish Diabetes Risk Score (FINDRISC) respectively. RESULTS: In a group of men with low risk of DM prevailed subjects with low-moderate CVR; every fourth person in this group had high and every tenth - very high CVR. In the group of men with moderately high risk of DM every second subject had high and every third - very high CVR. In the group of men with high and very high risk of DM every second subject had very high CVR. DM risk correlated most closely with metabolic risk factors. Less pronounced but significant correlation existed between levels of DM and CVR risk and parameters of arterial pressure, lipid spectrum, age, and sedentary lifestyle. There was no significant correlation between DM risk and left ventricular hypertrophy, smoking, and tachycardia. CONCLUSION: Highest rate of very high CVR was revealed among men with high and very high risk of DM, while rate of high CVR in groups with moderately high and high risk of DM appeared to be comparable.