A case of epithelioid hemangioendothelioma of the mandibular bone

This report describes the case of 44-year-old man with sensory paralysis of the left side of the lower lip who visited our hospital. An orthopantomographic examination showed an ill-defined radiolucency around the left mental foramen. Angiography showed a beadlike-shadow surrounding the left mental foramen. Examination of a biopsy specimen suggested a hemangioma. Segmental resection of the mandibular bone was performed under general anesthesia. Histological examination revealed round or polygonal tumor cells, some of which showed mitotic figures. Immunohistological staining with FactorVIII related antigen showed tumor cells with distinctly positive findings. Histopathological examination resulted in a diagnosis of epithelioid hemangioendothelioma. Recurrence and metastasis have not been detected, and the patient's progress has been good as of 40 months after the operation.