Polymeric Titanium Oxychloride Sorbent for 188W/188Re Nuclide Pair Separation

Abstract The chemical synthesis conditions (TiCl4: iPrOH reagent ratio and reaction temperature scheme) were optimized for the preparation of polymeric titanium oxychloride sorbent which met the requirements for clinically useful 188W/188Re generator production, such as high W-adsorption capacity, high 188Re-elution yield, low 188W-breakthrough, and good mechanical stability. This polymeric material was formed by polycondensation of titanium-oxychloride units, the chemical formula of which was supposed as [OTiO (Ti40 Cl80 (OH) 80 (TiO2)95.60H2O) OTiO]n. The effect of the W-content of tungstate solution on the WO4 2− ion adsorption (with minimizing the poly-tungstate ion adsorption) and its covalent bonding with the Ti metal atoms in the polymeric matrix were justified with respect to the optimal W-adsorption conditions for the preparation of a useful 188W/188Re generator column. The high W-adsorption capacity of about 515.6 mg W/g sorbent and 188Re elution yield of higher than 85% wereachieved. The large ...