Circulating thyroid hormones with serum uric acid and creatinine in hypo and hyperthyroidism

Introduction: Thyroid dysfunction is related to damaging effect on glomerular and tubular functions. In recent studies it was found that hypo and hyperthyroidism was accompanied with renal derangement resulting in abnormal levels of serum creatinine and uric acid. So this study was conducted for estimation of serum non-protein nitrogenous constituents in hypo and hyperthyroidism. Materials and Method: 60 patients, with 30 hypothyroid and 30 hyperthyroid patients were included in this study along with 30 controls. Thyroid hormones (T3, T4, and TSH) were estimated by Beckman coulter Access-2 immunoassay analyser. Uric acid, creatinine and urea parameters were measured using fully automated Beckman coulter clinical chemistry analyser AU480. Analysis of Statistical data was done by SPSS 20. Results: There was a significant increase in the levels of serum uric acid and (p