NF-κB p50 ( nfkb1 ) contributes to pathogenesis in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia

To the editor: Chronic lymphocytic leukemia (CLL) exhibits an indolent precursor phase prior to development of a more aggressive phenotype which requires treatment. Understanding the early pathogenesis of CLL offers the opportunity to better implement more effective intervention for this disease.