Synthesis of Optically Active Tertiary Silanes via Pd-Catalyzed Enantioselective Arylation of Secondary Silanes.

We herein describe the development of an efficient enantioselective catalytic system that promotes the arylation of secondary silanes. Our method involves treatment of secondary silanes and aryl iodides with a Pd2(dba)3–asymmetric phosphoramidite ligand system to afford optically active tertiary silanes with good enantioselectivities.