Диагностические возможности кардиопульмонального нагрузочного тестирования у пациентов с саркоидозом

A review of protocols and staging of cardiopulmonary exercise testing (CPET) used in clinical practice is done in the article. CPET is proposed to assess the functional status and to diagnose early reserve abnormalities in patients with sarcoidosis as far as functional tests at rest are mostly insufficient in sarcoidosis. Physiological processes at anaerobic threshold at peak exercise are described in the article. The authors reviewed current approach to terminology and determination of anaerobic threshold, methods for calculation of cut-off points and their clinical role. Diagnostic values of CPET parameters, such as maximal and peak oxygen uptake and oxygen consumption ratio, parameters of gas exchange and ventilation, such as ventilatory equivalent, breathing reserve, alveolar-arterial gradient in oxygen, and ventilation-perfusion ratio, in patients with sarcoidosis were also discussed.