Response to Comment on Lacy et al. Long-term Glycemic Control and Dementia Risk in Type 1 Diabetes. Diabetes Care 2018;41:2339–2345

We thank Medrano-De-Avila et al. (1) for their interest in our study (2) on long-term glycemic control and dementia risk among older adults with type 1 diabetes. In our study, the principal finding was that individuals with majority exposure to HbA1c 8–8.9% or HbA1c ≥9% had higher rates of dementia. A secondary finding was the suggestion that majority exposure to HbA1c <6% was potentially associated with a slightly (albeit statistically nonsignificant) increased risk of dementia. As Medrano-De-Avila et al. point out, prior studies have identified an association between hypoglycemia and dementia in …