Regioselective Synthesis of Ceralure B1 and A, Ethyl cis‐(and trans‐) 5‐Iodo‐trans‐2‐methylcyclohexane‐1‐carboxylate.

Abstract Reaction of trans -2-methyl-6-oxabicyclo[3.2.1]octan-7-one with trimethylsilyl iodide, generated in situ, followed by refluxing with ethanol gives regioselectively ethyl cis -(and trans -) 5-iodo-2-methylcyclohexane-1-carboxylate, a persistent attractant for male Mediterranean fruit flies.