Anti-inflammatory and analgesic activities of Dashanga Ghana: An Ayurvedic compound formulation

Background and Objectives : Inflammation is the self-protective reaction of tissues towards infection, irritants, or foreign substances. Though it is a part of host defence mechanism, when it becomes severe, it turns out to be a hopeless condition which causes damage of tissues; hence control of inflammation becomes essential. In Ayurvedic texts, a number of medicinal preparations to combat inflammation have been found; among them, Dashanga Yoga is one, which is said to be significant in combating inflammation. To revalidate this claim, the present experimental study was undertaken. Materials and Methods : Wistar strain albino rats weighing 200 ± 20 g and Swiss albino mice (26 ± 2 g) of either sex were used in the study. Pharmacologically validated models were used to evaluate anti-inflammatory and analgesic effects. Dashanga Yoga was administered at dose of 45 mg/kg and 65 mg/kg for rat and mouse, respectively. Results : Dashanga Yoga significantly inhibited carrageenan-induced paw edema ( P Conclusion : The results revealed that Dashanga Yoga has anti-inflammatory and analgesic activity. Hence, it can be used in the management of pain and inflammatory conditions.