Bowen's disease of the periorbital area.

We reported a 72-year-old women with Bowen's disease around the right periorbital area involving the conjunctiva. A tumor resected on her right upper eyelid margin at an ophthalmological clinic, 11 years ago. Furthermore, anoperation was performed for blepharoptosis and symblepharon at the Department of Ophthalmology in our hospital. However, symblepharon had recurred, and shedeveloped an erythematous lesion around her right periorbital area. Histopathological examination revealed that it was Bowen's disease (SCC in situ) . Tumor cells invaded to the conjunctival and corneal epithelum, but not to the dermis nor submucosa. We speculated the first operation may be the cause of dissemination of the tumor cells to the conjunctiva, and the development of this eccentric manifestation. [Skin Cancer (Japan) 2001; 16: 41-43]