Modified radial-search algorithm for segmentation of tibiofemoral cartilage in MR images of patients with subchondral lesion

Purpose The quantitative analysis of weight-bearing articular cartilage superficial to subchondral abnormality is important in osteoarthritis (OA) progression studies. The current study aimed to address the challenges of a semi-automatic segmentation of tibiofemoral cartilage in MR images of OA patient with and without subchondral bone abnormalities (SBA).