Colorectal Cancer Metastasis: The DNA Repair Inhibitor Dbait Increases Sensitivity to Hyperthermia and Improves Efficacy of Radiofrequency Ablation

Flavien Devun,Julian Biau,Michel Huerre,Amélie Croset,Jian-Sheng Sun,Alban Denys,Marie Dutreix

Colorectal Cancer Metastasis: The DNA Repair Inhibitor Dbait Increases Sensitivity to Hyperthermia and Improves Efficacy of Radiofrequency Ablation

2014

Flavien Devun
Julian Biau
Michel Huerre
Amélie Croset
Jian-Sheng Sun
Alban Denys
Marie Dutreix

DNA repair inhibition with Dbait sensitizes colorectal cancer cells to mild hyperthermia and could be used to improve clinical results of radiofrequency ablation as demonstrated in the animal model.

Keywords:

Radiofrequency ablation
Animal model
DNA Repair Inhibition
Colorectal cancer
Hyperthermia
Metastasis
DNA repair
Medicine
Internal medicine
Oncology
mild hyperthermia

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