Altered NMDA receptor expression and behavior following postnatal hypoxia: potential relevance to schizophrenia.

Andrea Schmitt,Markus Fendt,Mathias Zink,U. Ebert,M. Starke,M. Berthold,Anne Herb,Georg A. Petroianu,Peter Falkai,Fritz A. Henn

Altered NMDA receptor expression and behavior following postnatal hypoxia: potential relevance to schizophrenia.

2007

Andrea Schmitt
Markus Fendt
Mathias Zink
U. Ebert
M. Starke
M. Berthold
Anne Herb
Georg A. Petroianu
Peter Falkai
Fritz A. Henn

The present study investigated the effects of chronic, repeated hypoxia during a postnatal vulnerable period. Acoustic startle response in adult rats was measured along with NMDA receptor binding and mRNA expression of subunits at postnatal days (PND) 11 and 120.

Keywords:

Gene expression
Startle response
Nucleus accumbens
Prepulse inhibition
Animal model
Hypoxia (medical)
NMDA receptor
Schizophrenia
Biology
Internal medicine
Endocrinology
Hippocampal formation
Hippocampus
Downregulation and upregulation

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