Cutaneous precursor B-cell lymphoblastic lymphoma/leukemia: a case report

A 59-year-old man presented with a 3-month history of infiltrated aching nodules and plaques all over the body.Physical examination revealed multiple firm,erythematous nodules and plaques with marked tenderness on the trunk and limbs.Histopathological examination showed that there was a diffuse infiltrate of unique lymphoid cells with dark-stained nuclei and dust-like chromatin in the dermis and subdermis.Immunophenotype analysis showed that the tumor cells were diffusely positive for CD20,CD79a,CD10,terminal deoxynucleotidyl transferase (TdT),PAX5,and tor Ki-67 (70％).Bone marrow examination revealed an active proliferation of bone marrow cells,which were predominated by lymphocytes,with lymphoblasts and prolymphocytes accounting for 66％.The patient was diagnosed with cutaneous precursor B-cell lymphoblastic lymphoma/leukemia. Key words: B-cell lymphoblastic, precursor, Lymphoma;  Leukemia;  Immunophenotyping