Severity of inflammation as a risk factor for ileo-anal anastomotic leak after a pouch procedure in ulcerative colitis.

Purpose The pelvic pouch procedure (PPP) carries significant post-operative complication risks including a 4–14 % risk of ileo-anal anastomotic (IAA) leak [1–4]. The aim of this study is to evaluate the severity of disease at the distal resection margin as an independent risk factor for an IAA leak following the PPP for patients with ulcerative colitis (UC).