SIMPLE ENDOMETRIAL HYPERPLASIA - POST TAMOXIFEN THERAPY IN A PATIENT OF CARCINOMA BREAST

Tamoxifen is one of the modalities in the treatment for breast cancer, especially in postmenopausal patients. It acts primarily as an anti-estrogenic agent, due to its cytoplasmic estrogen receptor binding capacity. However, the same also exerts a mild estrogenic effect. Here with a case of ER positive carcinoma breast treated with Tamoxifen for 5 years, presented as post- menopausal bleeding per vaginum, showed an enhanced mass occupying the endometrial cavity, measuring >30mm is presented. Total hysterectomy was done.