Augmented Renal Clearance of Vancomycin and Levetiracetam in a Traumatic Brain Injury Patient

Background Increased creatinine clearance and subsequent elevated antimicrobial clearance is evident in many traumatic brain injury (TBI) patients due to augmented renal clearance (ARC). Little is known about the effects of ARC on other renally-eliminated medications, such as the anti-epileptic drug levetiracetam.