Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication:

Ilaria Vicenti,Filippo Dragoni,Alessia Giannini,Federica Giammarino,Michele Spinicci,Francesco Saladini,Adele Boccuto,Maurizio Zazzi

Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication:

2020

Ilaria Vicenti
Filippo Dragoni
Alessia Giannini
Federica Giammarino
Michele Spinicci
Francesco Saladini
Adele Boccuto
Maurizio Zazzi

Practical cell-based assays can accelerate anti-Zika (ZIKV) and anti-dengue (DENV) virus drug discovery. We developed an immunodetection assay (IA), using a pan-flaviviral monoclonal antibody recog...

Keywords:

Virus
Cell
Monoclonal antibody
Drug discovery
Biology
Flavivirus
Dengue virus
Virology
Virus quantification
cell based

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